Description
Darbepoetin, sold under the brand name Zynesp, It is licensed for the treatment of anemia caused by kidney failure or chemotherapy.
Darbepoetin alfa binds to the erythropoietin receptor on erythroid progenitor cells, stimulating RBC production and differentiation. Darbepoetin alfa is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88, T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition. It stimulates erythropoiesis (increases red blood cell levels) by the same mechanism as rHuEpo (binding and activating the Epo receptor) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy.
The medication was approved in September 2001, by the US Food and Drug Administration for treatment of anemia in patients with chronic kidney failure by intravenous or subcutaneous injection.[4] In June 2001, it had been approved by the European Medicines Agency for this indication as well as the treatment of anemia in cancer patients undergoing chemotherapy.
Branded Generic Drugs for Darbepoetin alfa Injection: Actorise | Bionesp | Cresp | Daptobio | Darbecept | Darbilen | Derise | Zynesp
NEWS / Updates
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hematopoietic agents, 12th edition, 1071 – 1072.
- Amgen Europe BV, Electronic medicines compendium (EMC), [Revised on Feb 2021] [Accessed on 13th Aug 2021], https://www.medicines.org.uk/emc/files/pil.6958.pdf
- Anna Maria Libudzic-Nowak et al., Darbepoetin Alfa in Young Infants With Renal Failure: Single Center Experience, a Case Series and Review of the Literature, Sec. Pediatric Nephrology, Published on 18th Dec 2018, Accessed on 13th Aug 2022, https://www.frontiersin.org/articles/10.3389/fped.2018.00398/full
Written By
Mr. Sandeep Tomar (D. pharma)
Last updated
26 Sep 2024 | 05:03 AM (IST)
FAQs
Is Zynesp (Darbepoetin) Injection launched in India?
Yes, Zynesp (Darbepoetin) Injection has been launched in India. It is available with Aark Pharmaceuticals.
What’s the cost price of Zynesp (Darbepoetin) Injection ?
Patients with a valid prescription, can send a request at Aark to get the best price of Zynesp (Darbepoetin) Injection in India. It can be delivered anywhere in India within 24-48 hours.
How to get Zynesp (Darbepoetin) Injection from Specialty Medicine Distributor in India?
Zynesp (Darbepoetin) Injection is available in India, to get or place an order from Specialty Medicine Distributor in India, please call us at+91 9999156233, You can also make an inquiry by emailing us at sales@aarkpharma.co.in, sales@aarkpharma.com, WhatsApp: +91 9999156233.
Note: Prior to consuming any medications, including “Darbepoetin Injection”, it is advisable to seek guidance from a medical professional regarding its therapeutic advantages, usage instructions, and potential side effects.
Get Access In India
How to get access to FDA approved Zynesp (Darbepoetin) Injection in India?
Aark can help you to get access prescription medicines for personal use, FDA approved Zynesp (Darbepoetin) Injection in India. We have delivered Anti-cancer medicines – Zynesp (Darbepoetin) Injection to following cities in India – Ahmedabad, Bangalore, Surat, Kolkata, Pune, Indore, Nagpur, Agra, Kanpur, Patna, Coimbatore, Kochi, Delhi, Gurugram, Amaravati, Itanagar, Dispur, Patna, Raipur, Panaji, Gandhinagar, Chandigarh, Shimla, Ranchi, Bengaluru, Thiruvananthapuram, Bhopal, Mumbai, Imphal, Shillong, Aizawl, Kohima, Bhubaneswar, Jaipur, Gangtok, Chennai, Hyderabad, Agartala, Lucknow, Dehradun, Gairsain. Aizawal, Aurangabad, Barshi, Cachar, Dibrugarh, Karungapally, Kollam, Meghalaya, Mizoram, Sikkim, Pondichery, Punjab, Tripura, New Delhi, Agra, Gurugram, Alwar, Mathura, Panipat, Faridabad, Noida, Sonipat, Rohtak, Karnal, Ambala, Ghaziabad.
Disclaimer
Disclaimer: We hereby declare that Aark Pharmaceuticals exclusively exports biosimilars or generic medicines manufactured in India. We do not export products manufactured by multinational companies. Our commitment lies in offering cost-effective healthcare solutions through generic medications, ensuring accessibility and affordability for all our customers. For any inquiries or assistance regarding our product range, please feel free to contact us.