Description
Darbepoetin Brand names available in India?
Darbepoetin is the generic name of the medication and is its international nonproprietary name. Darbepoetin is marketed under the brand name Zynesp among others. Darbepoetin, It is licensed for the treatment of anemia caused by kidney failure or chemotherapy.
Darbepoetin alfa binds to the erythropoietin receptor on erythroid progenitor cells, stimulating RBC production and differentiation. Darbepoetin alfa is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88, T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition. It stimulates erythropoiesis (increases red blood cell levels) by the same mechanism as rHuEpo (binding and activating the Epo receptor) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy.
The medication was approved in September 2001, by the US Food and Drug Administration for treatment of anemia in patients with chronic kidney failure by intravenous or subcutaneous injection.[4] In June 2001, it had been approved by the European Medicines Agency for this indication as well as the treatment of anemia in cancer patients undergoing chemotherapy.
Will this product be accessible across all regions of India?
The product – Zynesp (Darbepoetin) Injection will be available across India on request. Darbepoetin is available in all the major cities in India – Delhi, Chandigarh, Jodhpur, Patna, Kolkata, Lucknow, Hyderabad, Chennai, Ahmedabad, Bangalore, and Pune. To get or place an order from Aark Pharmaceuticals, a pharma distributor in India, please call us at+91 9999156233, You can also make an inquiry by emailing us at sales@aarkpharma.co.in, sales@aarkpharma.com, WhatsApp: +91 9999156233.
List of available brand-name drugs in India for Darbepoetin alfa Injection
Branded Generic Drugs for Darbepoetin alfa Injection: Actorise | Bionesp | Cresp | Daptobio | Darbecept | Darbilen | Derise | Zynesp
NEWS / Updates
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hematopoietic agents, 12th edition, 1071 – 1072.
- Amgen Europe BV, Electronic medicines compendium (EMC), [Revised on Feb 2021] [Accessed on 13th Aug 2021], https://www.medicines.org.uk/emc/files/pil.6958.pdf
- Anna Maria Libudzic-Nowak et al., Darbepoetin Alfa in Young Infants With Renal Failure: Single Center Experience, a Case Series and Review of the Literature, Sec. Pediatric Nephrology, Published on 18th Dec 2018, Accessed on 13th Aug 2022, https://www.frontiersin.org/articles/10.3389/fped.2018.00398/full
Written By
Mr. Sandeep Tomar (D. pharma)
Last updated
26 Sep 2024 | 05:03 AM (IST)